We go through "Blocks" (units) which each cover an organ system, except the first one (Block A) which is public health.
Molecules/biochem/genetics come up as relevant to each organ system. So, for example Block B is Respiration so the genetics focuses on genetic defects of the lungs, mutations in genes (enzymes, etc. related to this) pertinent to this, etc.. Molecules have a bigger role I'd say in Block E (Gastro) and F (immunology). Endocrine is mostly in Block E (Gastro) when we learn about diabetes, the thyroid (though it does come up briefly in other blocks as well).
There is a final exam after each block, which focuses on that organ system. The longer blocks will have a midterm. R&E is then a cumulative exam, it's during "R&E week": The final exam for the most recent block you did, the R&E exam, and the anatomy exam covering the most recent blocks you haven't been tested on are all during the same week. So for example, our first R&E 'week' was in December. We had a final exam for Cardio (Block C), an anatomy exam that covered the anatomy from Blocks B and C (resp and cardio), and R&E exam (covered Blocks A,B and C) during that last week of school. Our second R&E week had the final exam for Block E (gastro), anatomy exam covering Blocks D (renal) and E, and then an R&E exam. This second R&E exam covered topics from all the previous blocks, but with an emphasis on the most recent ones (D and E). Final exams are more detailed, R&E is supposed to be more broad.
So, right now we're covering infection (Block G. We just finished immunology, Block F), and next is Block H (movement). So we'll have final exams after Blocks F and G, and then to end first year we'll have a final R&E week during which we will have a final exam for Block H, an anatomy exam and an R&E exam (emphasis on the most recent blocks that have not yet been on an R&E exam).
Hope that makes sense