Khan Academy Orgo Question Mcat: Synthesis Of Anti-Tumor Drug Combretastatin And Its Derivatives

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Passage title: Synthesis of anti-tumor drug Combretastatin and its derivatives

Passage Section: CHEMICAL AND PHYSICAL FOUNDATIONS OF BIOLOGICAL SYSTEMS PASSAGES 

 

Hello everyone, 

 

I still do not understand the purpose of HCl in the question. Can somebody explain to me the mechanism behind why HCl is used or which standard reaction in follows from the prep books?

 

Thank you so much!

Synthesis of anti-tumor drug Combretastatin and its derivatives _ Chemical and physical sciences practice passage questions _ Chemical and Physical Foundations of Biological Systems Passages _ MCAT _ Khan Academy.pdf