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Good pre-req sGPA but bad upper-year level science course GPA, where do I stand?


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As indicated above in the title,

What if my GPA for pre-req science courses (i.e. intro bio, chem, calculus statistics, organic chem, bchems) are mostly in A/A+ range but my upper-year random science courses (ecology/biology/molecular biology etc...) are in B/C+ range? Would this have extremely negative consequences on my evaluation?

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