kylamonkey Posted September 6, 2011 Report Share Posted September 6, 2011 "Fatigue is biochemical, not biomechanical" - Andrew Coggan, PhD Discuss. Link to comment Share on other sites More sharing options...
future_doc Posted September 6, 2011 Report Share Posted September 6, 2011 Fatigue can be emotional, mental and physical, one alone or a combo when exerting yourself in a strenuous physical activity. I know what I am capable of and never let fatigue get in the way of achieving the particular goal I have set. Don't know if this is relevant to the discussion you are seeking. Link to comment Share on other sites More sharing options...
future_doc Posted September 7, 2011 Report Share Posted September 7, 2011 so far ... Link to comment Share on other sites More sharing options...
aaronjw Posted September 7, 2011 Report Share Posted September 7, 2011 Interesting and quite possible. In men, when they are overtrained (numerous factors account for this) their tesosterone levels plummet so for a particular situation where this was happening, i'd agree with fatigue being biochemical. Actually come to think of it, i'd wager most fatigue (not just the im tired from a 30min run that most will claim as being fatigued) is biochemical. Few instances are mechanically related. Interesting perspective. Link to comment Share on other sites More sharing options...
kylamonkey Posted September 7, 2011 Author Report Share Posted September 7, 2011 See, from my perspective I think about fatigue after a 10-hr run. If I've fueled properly (had complex sugars like maltodextrin, enough water, and the proper balance of electrolytes) I'm still good to go. If not- I'll be dizzy and trowing up and pissed off. That said, there's a certain point on, like, day 3 of a 6-day race where no amount of proper nutrition planning is going to change that your legs are just tired. Link to comment Share on other sites More sharing options...
Erk Posted September 7, 2011 Report Share Posted September 7, 2011 As a biochemist, I've generally thought this was self-evident, but I realise a fair bit of that might just be aggrandising my old field. Link to comment Share on other sites More sharing options...
Minion Posted September 7, 2011 Report Share Posted September 7, 2011 Fatigue is interesting because there are so many factors that effect it. You should look into Tim Noakes and his concept of central governor. http://www.ncbi.nlm.nih.gov/pubmed/17465612 Fatigue and exercise has some very interesting stuff going on right now. Link to comment Share on other sites More sharing options...
LostLamb Posted September 7, 2011 Report Share Posted September 7, 2011 Since my thesis depended on the statement posted by the OP, i say, yes, it is biochemical....and my lab has some physiological studies to prove it! and that is all i am gonna say about that. I've moved on. Too exhausted to try to explain/defend. Link to comment Share on other sites More sharing options...
apache Posted September 7, 2011 Report Share Posted September 7, 2011 interestingly enough it may be... i'll take a brain based look at it and say we also have to look at "perceptions of fatigue" versus actual muscle fatigue... almost like giving morphine to someone with a broken leg... one of the side effects of the amphetamines can be increased aggressiveness, competitiveness, anger, persistence, obsession (say to finnish a race), and a suppression of pain perception, via enkephalinss and other endogenous opiates may be seen in people with type a personality types, or people trained to be this way, like they're naturally "dopamined-up" all the time because of their habits, beliefs about themselves, competitive environment etc. Fatigue can be emotional, mental and physical, one alone or a combo when exerting yourself in a strenuous physical activity. I know what I am capable of and never let fatigue get in the way of achieving the particular goal I have set. Don't know if this is relevant to the discussion you are seeking. Link to comment Share on other sites More sharing options...
Cerena Posted September 8, 2011 Report Share Posted September 8, 2011 interestingly enough it may be... i'll take a brain based look at it and say we also have to look at "perceptions of fatigue" versus actual muscle fatigue... almost like giving morphine to someone with a broken leg... one of the side effects of the amphetamines can be increased aggressiveness, competitiveness, anger, persistence, obsession (say to finnish a race), and a suppression of pain perception, via enkephalinss and other endogenous opiates may be seen in people with type a personality types, or people trained to be this way, like they're naturally "dopamined-up" all the time because of their habits, beliefs about themselves, competitive environment etc. That's so interesting! Thnx muse Link to comment Share on other sites More sharing options...
Erk Posted September 8, 2011 Report Share Posted September 8, 2011 interestingly enough it may be... i'll take a brain based look at it and say we also have to look at "perceptions of fatigue" versus actual muscle fatigue... almost like giving morphine to someone with a broken leg... one of the side effects of the amphetamines can be increased aggressiveness, competitiveness, anger, persistence, obsession (say to finnish a race), and a suppression of pain perception, via enkephalinss and other endogenous opiates may be seen in people with type a personality types, or people trained to be this way, like they're naturally "dopamined-up" all the time because of their habits, beliefs about themselves, competitive environment etc. Your last line is a bit telling. I wonder how much of that training actually boils down to biochemical patterns in the brain. What we call 'training' can be summarised as changes in receptor and neurotransmitter expression over time through feedback loops. I suspect at least half of central command fatigue (what you're describing) is still biochemical. The rest, well, we still don't know the brain well enough to say. I do completely agree with your statement, I just wanted to blab a little. Basically, attributing a portion of fatigue to neurology is still biochemical rather than mechanical. Link to comment Share on other sites More sharing options...
apache Posted September 8, 2011 Report Share Posted September 8, 2011 lol, i love the hard problem... there's really no sure answer The rest, well, we still don't know the brain well enough to say. Link to comment Share on other sites More sharing options...
Recommended Posts
Archived
This topic is now archived and is closed to further replies.